Small airway function

Alvesco^® improves small airway function.^1-3 It significantly reduces small airway resistance and eosinophilic inflammation; this is in contrast to fluticasone propionate DPI² (Figure 1). Read more

Figure 1: Alvesco^® reduces the percentage of eosinophils in late-phase (small-airways-sampled) sputum²

Alvesco^® also significantly increases Asthma Control Test™ (ACT) scores² (Figure 2) and reduces small airway hyperresponsiveness.³ Read more

Figure 2: Alvesco^® increases Asthma Control Test (ACT) scores²

See the section on Targeting small airways for more information on how Alvesco^® targets this lung region.

References:

1. Cohen J, Douma WR, ten Hacken NH, et al. Ciclesonide improves measures of small airway involvement in asthma. Eur Respir J 2008;31:1213-1220
2. Hoshino M. Comparison of effectiveness in ciclesonide and fluticasone propionate on small airway function in mild asthma. Allergol Int 2010;59:59-66
3. Cohen J, Postma DS, Douma WR, et al. Particle size matters: diagnostics and treatment of small airways involvement in asthma. Eur Respir J 2011;37:532-540